Eating

The GLP-1 nutrition guide: what to eat, drink and watch

By Jeff Zorn, founder of Zornava. Former college basketball player, degree in exercise science and nutrition, two years on GLP-1 medications. My experience, not medical advice. Talk to your prescriber or a registered dietitian about your own situation.

Published · Last reviewed

Short answer: on a GLP-1 medication people eat 16% to 39% less, so each small meal has to carry more.[1] Put protein first, add fiber from food slowly, drink on a schedule rather than on thirst, and watch the nutrients a 2025 joint advisory flags as at risk, such as vitamin D, calcium and B12.[1]

This page is a map. Each section below answers one question in a few lines and points to the article that covers it in full, with its own sources. If you would rather read one long piece from start to finish, start with our guide to what to eat when you're eating less; this page sorts the same ground by question.

What are the key numbers on a GLP-1?

None of these numbers is specific to GLP-1 medications. They are the general reference intakes for healthy adults, and the starting point the detailed articles work from. Your clinician's figure replaces any of them if you have one.

What Reference for adults The full article
Protein 0.8 g per kg of body weight a day (RDA); 1.2 to 1.6 g/kg proposed while weight is coming down[1][2] How much protein on a GLP-1
Fiber 14 g per 1,000 calories eaten; the label Daily Value is 28 g[3][4] How much fiber a day on a GLP-1
Fluid from drinks about 2.2 L (9 cups) a day for women, 3 L (13 cups) for men[5] How much water to drink on a GLP-1
Sodium, potassium, magnesium Daily Values of 2,300 mg, 4,700 mg and 420 mg[4] How to choose an electrolyte drink
Vitamins and minerals vitamin D, calcium and B12 are the ones the advisory names as worth considering[1] Which vitamins matter on a GLP-1

What should you eat on a GLP-1?

There is no official GLP-1 diet. The pattern the 2025 advisory describes is ordinary healthy eating in smaller amounts, built around protein, with fruit or vegetables and whole grains, and for unsettled days it suggests a small breakfast, then small meals every three to four hours with enough fluid.[1]

How much protein do you need on a GLP-1?

At least the RDA of 0.8 g per kilogram of body weight a day, and the advisory notes that 1.2 to 1.6 g/kg has been proposed while body weight is coming down.[1][2] For a 75 kg (165 lb) adult that is 60 g at minimum and 90 to 120 g at the higher range. Protein comes first on the plate because low protein intake on a reduced appetite can add to muscle loss, and the advisory pairs it with resistance or strength training as the two measures for keeping muscle.[1]

How much fiber do you need on a GLP-1?

The Dietary Guidelines set 14 g for every 1,000 calories, about 20 g a day at 1,400 calories.[3] The difficulty is fitting it into much less food, and the advisory notes that fatty and high-fiber foods can be harder to tolerate in the first days of a new dose.[1] Build up slowly, from food first, with fluid alongside.

How much water should you drink, and do you need electrolytes?

The National Academies' reference is about 2.2 liters of drinks a day for women and 3 liters for men, more with activity or heat.[5] About 20% of water normally comes from food, so eating less removes some of it, and the prescribing labels warn that fluid lost through vomiting or diarrhea can lead to acute kidney injury.[5][6][7] Eating less also means less of the minerals that arrive with food, which is why sodium, potassium and magnesium come up on low-appetite days.

Which vitamins and minerals run low?

The advisory lists vitamins A, D, E, K, B1, B12 and C, plus iron, calcium, magnesium and zinc, as the nutrients most likely to fall short, and says supplements "can be proactively considered for at-risk nutrients, such as vitamin D, calcium, B12, or a multivitamin-mineral tablet, at appropriate doses and tailored to each person's needs".[1] A blood test tells you which apply to you.

For transparency about our own product: Zornava Replenish is a lemon-lime drink mix with sodium, potassium, magnesium and calcium, a prebiotic fiber (partially hydrolyzed guar gum) and vitamins C, D3, B1, B6, folate and B12 with zinc. It has no protein, no iron and no vitamins A, E or K, so it is not a meal or a multivitamin, and it sits beside the food in every section above rather than in place of it.

What about tiredness, hair shedding and queasy days?

Each of these is listed in at least one prescribing label, and each has a food-and-fluid side worth checking. In the Wegovy trials, 11% of adults reported fatigue or weakness against 5% on placebo.[6] In the Zepbound trials, fatigue was reported by 5% to 7% depending on dose against 3% on placebo, and hair loss by 4% to 5% against 1%.[7] The shedding usually described is telogen effluvium. A 2020 review notes that it can follow calorie restriction, generally starts two to three months after the trigger, and in its acute form lasts under six months and resolves in around 95% of cases.[8]

Is there a page for your medication?

Semaglutide is sold as Wegovy and Ozempic; tirzepatide as Zepbound and Mounjaro. The food advice is the same across them, but each label records different trial figures, so these pages quote the label for that drug.

Question Wegovy or Ozempic (semaglutide) Zepbound or Mounjaro (tirzepatide)
What to eat What to eat on Wegovy or Ozempic What to eat on Zepbound
Tiredness Does Wegovy or Ozempic make you tired? Does Zepbound make you tired?
Hair shedding GLP-1 medications and hair shedding Zepbound, Mounjaro and hair shedding
Staying regular Fiber and staying regular on a GLP-1 Zepbound: fiber, fluid and when to call

Retatrutide, nicknamed "GLP-3", is not approved yet. What its trials found and where approval stands are in GLP-3 (retatrutide) explained.

Which tools put numbers on your own day?

When should you talk to your prescriber?

When you cannot keep fluids down, are passing very little urine, feel faint on standing or confused, when tiredness is severe or does not ease, or when you are eating so little that a whole day goes by with almost nothing. Each detailed article ends with the signs specific to its topic. The advisory also points to a registered dietitian as one of the main supports for people on these medications.[1]

Not sure which part of your intake is slipping on lighter days? Our two-minute quiz sorts it into water, protein, fiber and vitamins.

Frequently asked questions

What should I eat on a GLP-1?

Small meals built around protein, with fruit or vegetables and whole grains, plus steady fluids. That is the pattern a 2025 joint advisory from four US medical and nutrition societies describes. There is no special diet.

How much protein do I need on a GLP-1?

At least 0.8 g per kilogram of body weight a day, the adult RDA. The 2025 advisory notes that 1.2 to 1.6 g/kg has been proposed while body weight is coming down. Your clinician's figure comes first if you have one.

How much water should I drink on a GLP-1?

The National Academies' reference is about 2.2 liters of drinks a day for women and 3 liters for men, more with activity or heat. Drinking on a schedule works better than waiting for thirst on these medications.

Which vitamins should I watch on a GLP-1?

The 2025 advisory names vitamin D, calcium and B12, or a multivitamin-mineral, as worth considering for at-risk nutrients. A blood test shows which ones apply to you.

Do I need a special supplement for a GLP-1?

No supplement is required, and none works like the medication. Supplements fill specific gaps that food leaves; which ones, if any, depends on what you eat and what your blood work shows.

References

  1. Mozaffarian D, Agarwal M, Aggarwal M, et al. Nutritional priorities to support GLP-1 therapy for obesity: a joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society. Obesity (Silver Spring). 2025;33(8):1475–1503. Full text. PMID: 40445127. doi: 10.1002/oby.24336. ↩︎
  2. Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. National Academies Press. 2005. nap.nationalacademies.org. doi: 10.17226/10490. ↩︎
  3. US Department of Agriculture and US Department of Health and Human Services. Dietary Guidelines for Americans, 2020–2025. Office of Disease Prevention and Health Promotion. 2020. odphp.health.gov. ↩︎
  4. US Food and Drug Administration. Daily Value on the Nutrition and Supplement Facts Labels. fda.gov. fda.gov. ↩︎
  5. Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. National Academies Press. 2005. nap.nationalacademies.org. doi: 10.17226/10925. ↩︎
  6. Novo Nordisk. Wegovy (semaglutide) injection and tablets, prescribing information and Medication Guide. DailyMed, US National Library of Medicine. 2026. (section 6.1) DailyMed. ↩︎
  7. Eli Lilly and Company. Zepbound (tirzepatide) injection, prescribing information and Medication Guide. DailyMed, US National Library of Medicine. 2026. (sections 5 and 6.1, Table 1) DailyMed. ↩︎
  8. Asghar F, Shamim N, Farooque U, et al. Telogen Effluvium: A Review of the Literature. Cureus. 2020;12(5):e8320. Full text. PMID: 32607303. doi: 10.7759/cureus.8320. ↩︎

Free guide

The GLP-1 eating plan

Eight pages to print and keep, built protein first for days when appetite is small. Sourced, like everything on Lighter Days.

  • Seven days of four small meals, with protein and fiber counted
  • A food list: what to eat more often, and what to go easy on
  • A shopping list and a page to take to your prescriber or dietitian

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