Nature Made GLP-1 Companion Health Pack vs Zornava Replenish: The Labels Side by Side
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Short answer: they are different kinds of product. Nature Made's GLP-1 Companion Health Pack is a daily packet of four pills, a multivitamin/mineral, magnesium, vitamin B12 and calcium with vitamin D3, that together list 22 vitamins and minerals and less than 1 g of fiber.[1][2] It costs $24.99 for 30 packets on Nature Made's site as of November 13, 2026.[3] Zornava Replenish is a lemon-lime powder you mix into water, built around fluids, electrolytes, 6 vitamins and 3.5 g of prebiotic fiber; it is not on sale yet.
New to eating less? Start with what to eat when you're eating less, the guide the rest of Lighter Days builds on.
Read this with one fact in mind: we make Replenish. That is why every Nature Made figure on this page comes from Nature Made's own product page and the Supplement Facts panel printed on its carton, linked in the references, and why nothing here says one product is better. The point is to put the two labels side by side so you can see what each one is for. Zornava is not affiliated with, sponsored by or endorsed by Nature Made or its maker, Pharmavite LLC. Nature Made is a trademark of its owner, named here only to identify the product.
General information, not medical advice. Which nutrients you need depends on what you eat, your blood work and your medications. A prescriber, pharmacist or registered dietitian can look over either label with you.
Nature Made GLP-1 Companion Health Pack vs Replenish at a glance
| Nature Made GLP-1 Companion Health Pack | Zornava Replenish | |
|---|---|---|
| Format | 4 pills in one daily packet: multivitamin/mineral, magnesium, vitamin B12, calcium + D3. Taken "with water and a meal"[2][1] | Lemon-lime powder, mixed into water and drunk |
| Servings per box or jar | 30 packets, a 30-day supply[3] | 30 servings |
| Vitamins | 13: A, C, D3, E, K, thiamin, riboflavin, niacin, B6, folate, B12, biotin, pantothenic acid[1] | Key Nutrients† (6 vitamins) |
| Minerals | 9: calcium, iodine, magnesium, zinc, selenium, copper, manganese, chromium, molybdenum. No sodium, potassium or iron listed[1] | Hydration† (4 electrolyte minerals plus zinc) |
| Fiber | Less than 1 g[1] | Prebiotic Fiber† (3.5 g PHGG, partially hydrolyzed guar gum) |
| Amounts per serving | Printed on the carton; full panel below[1] | Published with the final label; the formula is not yet confirmed |
| List price | $24.99 one-time; $22.49 with Subscribe & Save[3] | $59 one-time; $49 with a monthly subscription |
| Price per day | About $0.83 one-time, $0.75 on subscription | About $1.97 one-time, $1.63 on subscription |
| Who makes it | Nature Made, a Pharmavite LLC brand[3] | Zornava, the company that publishes this site |
| Availability (November 13, 2026) | On sale at naturemade.com and listed at grocery and pharmacy retailers[3][4] | Not on sale yet; early access opens February 9, 2027 |
Prices are list prices before tax, divided by 30 servings. Retailer prices for the Nature Made pack vary. Nature Made's product page says Subscribe & Save orders ship free;[3] Replenish ships free on subscription and costs $5.95 to ship on a one-time order.
What is in the Nature Made GLP-1 Companion Health Pack?
Four separate pills in one packet. The carton's side panel names them: a multivitamin/mineral, a magnesium pill, a vitamin B12 pill and a calcium + vitamin D3 pill.[2] The label's statement of identity is "multivitamin and mineral supplement", and the serving size is 1 packet.[2][1] Nature Made's page says the four can be taken together or split between meals, as long as the whole packet is taken each day with food.[3]
This is the Supplement Facts panel as printed on the back of the carton, for one packet:[1]
| Nutrient (form, as printed) | Amount per packet | % Daily Value |
|---|---|---|
| Total carbohydrate | less than 1 g | <1% |
| Dietary fiber | less than 1 g | 3% |
| Vitamin A (beta carotene and retinyl acetate) | 750 mcg | 83% |
| Vitamin C (ascorbic acid) | 180 mg | 200% |
| Vitamin D3 (cholecalciferol) | 35 mcg (1,400 IU) | 175% |
| Vitamin E (dl-alpha tocopheryl acetate) | 27 mg | 180% |
| Vitamin K (phytonadione) | 80 mcg | 67% |
| Thiamin (thiamine mononitrate) | 1.5 mg | 125% |
| Riboflavin | 1.7 mg | 131% |
| Niacin (niacinamide) | 20 mg | 125% |
| Vitamin B6 (pyridoxine hydrochloride) | 6 mg | 353% |
| Folate (400 mcg folic acid) | 665 mcg DFE | 167% |
| Vitamin B12 (cyanocobalamin) | 2,525 mcg | 105,208% |
| Biotin | 30 mcg | 100% |
| Pantothenic acid (d-calcium pantothenate) | 10 mg | 200% |
| Calcium (calcium carbonate and dibasic calcium phosphate) | 827 mg | 64% |
| Iodine (potassium iodide) | 150 mcg | 100% |
| Magnesium (magnesium oxide) | 350 mg | 83% |
| Zinc (zinc oxide) | 15 mg | 136% |
| Selenium (sodium selenate) | 70 mcg | 127% |
| Copper (copper sulfate) | 2 mg | 222% |
| Manganese (manganese sulfate) | 4 mg | 174% |
| Chromium (chromium chloride) | 120 mcg | 343% |
| Molybdenum (sodium molybdate) | 75 mcg | 167% |
Other ingredients, as printed: cellulose gel; less than 2% of maltodextrin, modified food starch, croscarmellose sodium, hypromellose, stearic acid, magnesium stearate, rice starch, isomalt, medium chain triglycerides, gelatin, polyethylene glycol, carnauba wax.[1]
Three things on that panel are worth understanding before you read it as a total for your day:
- The B12 percentage is large because the Daily Value is small. The Daily Value for B12 is 2.4 mcg,[5] so 2,525 mcg prints as 105,208%. No upper limit has been set for vitamin B12.[6]
- The magnesium equals the adult upper limit for magnesium from supplements, which is 350 mg a day.[7] That limit counts supplements only, not food, so it matters if you add any other product with magnesium in it, electrolyte drinks included.
- Iron and sodium and potassium are not on the panel. The pack has no iron,[1] and the 2025 joint advisory on nutrition with GLP-1 therapy lists iron among the nutrients of concern when intake falls.[8] If you need iron, that is a conversation with your clinician and a blood test, not a guess.
The label carries cautions too: consult a physician before use if you are pregnant, nursing, have kidney disease or blood clotting issues, or take medications, and "for adults taking GLP-1 medications, consult with your physician before taking any dietary supplements."[1][3] The same advice applies to any supplement, Replenish included.
What is in Zornava Replenish?
Zornava Replenish is a lemon-lime daily hydration and nutrient powder for lighter appetite days, including for people on GLP-1 medications. One jar holds 30 servings. Each serving is mixed into water, so the product is partly the drink itself. It is built around three things:
- Hydration†: 4 electrolyte minerals plus zinc.
- Key Nutrients†: 6 vitamins.
- Prebiotic Fiber†: 3.5 g of PHGG (partially hydrolyzed guar gum) per serving.
Per-ingredient amounts and % Daily Values are not printed here on purpose. The formula is not yet confirmed, and the full Supplement Facts panel will be published with the final label. Until then, hold Replenish to the same checklist as anything else, which is the approach in our guide to choosing an electrolyte drink on a GLP-1. Replenish is not built as a multivitamin, and it is not on sale yet: early access opens February 9, 2027, at $59 one-time or $49 a month on subscription, with a 60-day money-back guarantee.
Pills or powder: what is the real difference?
The two products answer different questions, which is why a straight "which wins" comparison does not work.
The Nature Made pack is a multivitamin-mineral routine in one packet. It covers a broad list of vitamins and minerals, with extra B12, magnesium, calcium and vitamin D in their own pills.[2] Those four line up with what the 2025 joint advisory names: it says supplements "can be proactively considered for at-risk nutrients, such as vitamin D, calcium, B12, or a multivitamin-mineral tablet", tailored to each person.[8] It brings almost no fiber and no fluid of its own beyond the water you swallow the pills with.
Replenish is a drink. Its focus is the other side of the same advisory: fluids and fiber. People taking GLP-1 medications eat 16% to 39% fewer calories, the advisory notes,[8] and normally about a fifth of the water people take in comes from food,[9] so eating less quietly means drinking less too. A powder adds a glass of fluid, electrolyte minerals and a measured dose of fiber, but only 6 vitamins, so it does not do the job of a multivitamin.
Practical differences follow from the format. Four pills a day suits people who swallow pills easily and want broad coverage. A drink suits people who would rather sip than swallow, or who already struggle to get enough fluid. Neither is a meal, and neither replaces protein, which is usually the biggest gap on a small appetite.[8]
Can you take the Nature Made pack and Replenish together?
Possibly, but add the labels up first, and do it with your prescriber or a dietitian. When two products overlap, the totals are what count:
- Magnesium. The Nature Made packet already supplies 350 mg, the adult upper limit for magnesium from supplements.[1][7] Any other product with magnesium, including an electrolyte drink, adds to that total.
- Zinc. The packet has 15 mg and Replenish contains zinc too. The adult upper limit for zinc is 40 mg a day from all sources.[1][10]
- Vitamins. Check every vitamin that appears on both labels once the Replenish panel is published, along with anything else you take.
Our guide to what supplements to take with a GLP-1 sets out how to build a short list without doubling up.
How to choose between them
Start from what you are missing, not from the box. A rough guide:
- You want a multivitamin-style routine with B12, vitamin D, calcium and magnesium covered, and you take pills easily: a multivitamin-mineral pack like Nature Made's is built for that. Read the totals against anything else you take. Our guide to what vitamins to take on a GLP-1 covers the evidence nutrient by nutrient.
- Fluids and fiber are the gap, because you drink little when you eat little, or meals have shrunk to the point that fiber has gone: a drink with electrolytes and fiber addresses that, and a pill pack does not. The hydration calculator gives a daily fluid figure, and our fiber comparison goes through the fiber types.
- Your blood work shows a specific shortfall, such as low B12, vitamin D or iron: a targeted supplement chosen with your clinician makes more sense than either general product.
- You are not sure: the nutrition gap calculator shows which nutrients a smaller plate tends to miss, and a prescriber, pharmacist or registered dietitian can look at either label against your diet and medications.
One more point that applies to both. The words "GLP-1" on a supplement describe who it is marketed to, not what it does: no supplement acts like the medication. Our explainer on GLP-1-branded supplements covers why, and how to read what is behind the name.
Frequently asked questions
What is in the Nature Made GLP-1 Companion Health Pack?
Each daily packet holds four pills: a multivitamin/mineral, magnesium, vitamin B12, and calcium with vitamin D3. Together the Supplement Facts panel lists 13 vitamins and 9 minerals, including 2,525 mcg of B12, 35 mcg (1,400 IU) of vitamin D3, 827 mg of calcium, 350 mg of magnesium and 15 mg of zinc, with less than 1 g of fiber.
How much does the Nature Made GLP-1 Companion Health Pack cost?
On Nature Made's site on November 13, 2026, a box of 30 packets was $24.99 one-time, or $22.49 with Subscribe & Save, about $0.83 or $0.75 a day. Retailer prices vary.
How many pills are in a Nature Made GLP-1 Companion packet?
Four. The label says to take the contents of one packet daily with water and a meal. Nature Made says the four can be taken together or split between meals, as long as the whole packet is taken each day with food.
Is Replenish a multivitamin?
No. Replenish is a lemon-lime hydration and nutrient powder with 4 electrolyte minerals plus zinc, 6 vitamins and 3.5 g of prebiotic fiber per serving. The Nature Made pack is a multivitamin and mineral supplement with 22 vitamins and minerals. They cover different ground.
Does the Nature Made GLP-1 Companion Health Pack have electrolytes?
It contains calcium and magnesium, which are electrolyte minerals, but sodium and potassium are not on its label, and it is taken as pills rather than mixed into a drink. For what to look for in an electrolyte drink, see our label-reading guide.
Can I take a multivitamin pack and an electrolyte drink together?
Often, but add up the overlapping nutrients first. The Nature Made packet alone supplies 350 mg of magnesium, the adult upper limit for magnesium from supplements, and 15 mg of zinc against a 40 mg upper limit. Ask your prescriber or a dietitian to check the totals.
Is Zornava affiliated with Nature Made?
No. Zornava is not affiliated with, sponsored by or endorsed by Nature Made or Pharmavite LLC. We make Replenish, and we took every Nature Made figure on this page from Nature Made's own product page and carton label.
When can I buy Replenish?
Not yet. Early access opens February 9, 2027. The price will be $59 one-time or $49 a month on subscription, for 30 servings, with a 60-day money-back guarantee.
References
- Nature Made (Pharmavite LLC). GLP-1 Companion Health Pack, carton back panel: Supplement Facts and other ingredients. naturemade.com. (Supplement Facts panel and other ingredients) naturemade.com. Label image published on the manufacturer’s product page, read 2026-11-13. Nature Made notes that products may change; the label on the product purchased is authoritative. ↩︎
- Nature Made (Pharmavite LLC). GLP-1 Companion Health Pack, carton side panel: the four supplements in each packet. naturemade.com. naturemade.com. Label image published on the manufacturer’s product page, read 2026-11-13. ↩︎
- Nature Made (Pharmavite LLC). GLP-1 Companion Health Pack Daily Packets. naturemade.com. (price, count, suggested use and cautions as shown on November 13, 2026) naturemade.com. Manufacturer’s product page (item HL000723), read 2026-11-13. Brand page, not peer-reviewed. ↩︎
- Food Lion. Nature Made GLP-1 Companion Health Pack Packets, 30 ct box. foodlion.com. foodlion.com. Retailer listing; confirms retail availability, the four supplements per packet and the other ingredients. No price shown on the listing on 2026-11-13. ↩︎
- US Food and Drug Administration. Daily Value on the Nutrition and Supplement Facts Labels. fda.gov. fda.gov. ↩︎
- Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Chapter 9, Vitamin B12. National Academies Press. 1998. nap.nationalacademies.org. doi: 10.17226/6015. ↩︎
- Institute of Medicine. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Chapter 6, Magnesium. National Academies Press. 1997. nap.nationalacademies.org. doi: 10.17226/5776. ↩︎
- Mozaffarian D, Agarwal M, Aggarwal M, et al. Nutritional priorities to support GLP-1 therapy for obesity: a joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society. Obesity (Silver Spring). 2025;33(8):1475–1503. (sections on supplements, fluids and nutrients of concern) Full text. PMID: 40445127. doi: 10.1002/oby.24336. ↩︎
- Institute of Medicine. Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. National Academies Press. 2005. nap.nationalacademies.org. doi: 10.17226/10925. ↩︎
- Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Chapter 12, Zinc. National Academies Press. 2001. nap.nationalacademies.org. doi: 10.17226/10026. ↩︎
